Control of a Mycoplasma pneumoniae Outbreak in an Institutional Setting Using Azithromycin Prophylaxis

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Control of a Mycoplasma pneumoniae Outbreak in an Institutional Setting Using Azithromycin Prophylaxis

Background Mycoplasma pneumoniae is a major cause of respiratory infection of varying severity. Outbreaks of M. pneumoniae infection commonly occur in closed or semi-closed communities and settings. The control of such outbreaks is challenging, owing to delayed detection, long incubation period, and paucity of infection control guidelines. Methods Between May and July 2015, a residential faci...

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Azithromycin prophylaxis during a hospital outbreak of Mycoplasma pneumoniae pneumonia.

Outbreaks of Mycoplasma pneumoniae (MP) in closed communities can have a high attack rate and can last several months. Azithromycin chemoprophylaxis has not been evaluated as a means of limiting transmission. This randomized, double-blinded placebo-controlled trial of azithromycin was conducted among asymptomatic hospital employees during an MP outbreak. Oropharyngeal swabs were obtained for de...

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Enhanced control of an outbreak of Mycoplasma pneumoniae pneumonia with azithromycin prophylaxis.

There are currently no recommended epidemic-control measures for Mycoplasma pneumoniae pneumonia outbreaks in closed communities. Previous studies have suggested the usefulness of chemoprophylaxis administered to close contacts of case-patients. To evaluate the effectiveness of various epidemic-control measures during an institutional outbreak, an observational study was undertaken during a ver...

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REFERENCES 1 Von Drygalski A, Curtis BR, Bougie DW, et al. Vancomycininduced immune thrombocytopenia. N Engl J Med 2007; 356: 904–910. 2 Documed. Product information dobutamine injection. Arzbeunuttel Kompendium der Schweiz. [Swiss Compendium of Therapeutic Drugs.] www.documed.ch Date last updated: 2005. Date last accessed: December 1, 2009. 3 George JN, Raskob GE, Shah SR, et al. Drug-induced ...

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ژورنال

عنوان ژورنال: Frontiers in Public Health

سال: 2018

ISSN: 2296-2565

DOI: 10.3389/fpubh.2017.00366